Phenibut HCl vs. FAA: Which Form is Better?

Phenibut is available on the market in two forms: phenibut HCl and phenibut FAA. The following is a comparison of the main differences between these two:
Chemical Form and Solubility
Phenibut HCl: This is the hydrochloride salt form of phenibut. It is more water-soluble and it’s easy to dissolve in liquids.
Phenibut FAA: This is the free amino acid form of phenibut. It is less water-soluble and more lipid-soluble.
Absorption and Bioavailability
Phenibut HCl: Due to its higher water solubility, phenibut HCl is generally absorbed more quickly in the digestive tract. However, the presence of the hydrochloride group can make it slightly more acidic, which might cause stomach discomfort in some individuals.
Phenibut FAA: Because it is less water-soluble, phenibut FAA may be absorbed more slowly. However, its higher lipid solubility allows it to be absorbed sublingually (under the tongue), which can lead to faster onset of effects.
Dosage
Phenibut HCl: The dosage is typically measured in milligrams (mg) and is often standardized. Users should be cautious with dosing due to its potency.
Phenibut FAA: Because it lacks the hydrochloride group, phenibut FAA has a slightly higher effective dose of the active compound in each milligram compared to the HCl form.
Taste and Administration
Phenibut HCl: It has a bitter and acidic taste, which can be unpleasant for some users. It is usually taken orally with water or another beverage.
Phenibut FAA: It has a less bitter taste and can be taken sublingually, which some users prefer for faster absorption and to avoid stomach discomfort.
Potential Side Effects
Phenibut HCl: The acidic nature of the hydrochloride salt can sometimes cause stomach upset or irritation in sensitive individuals.
Phenibut FAA: May be gentler on the stomach due to the absence of the hydrochloride group, but individual responses can vary.
Conclusion
Both phenibut HCl and FAA are effective, but the choice between them may depend on individual preferences, sensitivity to stomach acidity, and desired method of administration. Always use phenibut responsibly, as it can be habit-forming and has potential for withdrawal symptoms with prolonged use.