If you search for phenibut on Amazon, you will get many results of various nootropic supplements, but none of them is actually phenibut. Well, don’t bother! Amazon no longer allows the sale of phenibut and a whole bunch of other nootropic drugs, particularly piracetam and its analogues.
Yes, Amazon is a great place to source many herbal and natural supplements, but phenibut is just the opposite of that! It is a synthetic chemical that is treated as a drug in some countries, and so it is not considered a dietary supplement according to FDA regulations.
Phenibut is not an approved supplement or medication in the US and worldwide, except in a few countries where it is an approved treatment (Russia, Ukraine and Latvia). It is also not a scheduled or regulated substance, which means that consumers can legally purchase it over the counter.
Although Amazon decided not to deal with such drug/supplement products, there are still many other reliable places online that sell phenibut.
Where to Buy Phenibut?
UPDATE: Following recent FDA-issued warnings to manufacturers wrongly labeling phenibut as a dietary supplement, many stores have stopped selling it. As of yet, phenibut is not banned, but it’s not permissible in products labeled as a dietary supplement. It is a synthetic nootropic compound that should be used with caution (more details can be found below).
The following are seven of the best legit vendors that still carry phenibut. You will also find numerous other nootropics that are banned on Amazon available at the following stores.
|Vendor||Capsule Price||Powder Price|
|Nootropics Depot||$14.99 (60 x 250mg)||$17.99 (25g)|
|Note: This is the go-to vendor where you can find any nootropic supplement. They excel in customer service and quality control.|
|Hard Rhino||$9.99 (90 x 250mg)||$24.99 (125g)|
|Note: This is a bulk supplement supplier that carries various categories of products at relatively low prices. They also have a good collection of CBD capsules and tinctures.|
|$13.88 (70 x 300mg)||$33.88 (100g)|
|Note: A long-established retailer of many natural and synthetic nootropics. They offer various forms of phenibut with good quality and reasonable prices.|
|Health Naturals||$17.99 (100 x 250mg)||[No powder]|
|Note: A good vendor where you can find several capped nootropics at affordable prices. They only ship to the USA and Canada.|
|SuperSmart||$39.00 (60 x 500mg)||[No powder]|
|Note: One of the leading online supplement stores in Europe. They ship globally, but unless you live in the UK or EU, you should stick with US vendors as they are cheaper.|
|Raw Powders||$43.61 (90 x 500mg)||$37.37 (50g)|
|Note: A European retailer based in Lithuania. Their phenibut capsules are non-vegan. Prices are higher than other shops, but they deliver faster to the UK and European countries.|
|BodyShock.pro||$29.86 (90 x 500mg)||$38.08 (100g)|
|Note: This is a Polish retailer of many supplement brands from Europe and the USA. They sell pure phenibut from Revange Nutrition, as well as other brands of powder formulas that contain phenibut.|
Where to Buy Brand Phenibut (Noofen)?
Phenibut is sold as a prescription medicine in some parts of the world, particularly Russian and other former Soviet Union countries. It is sold under different brand and generic names in 250mg tablets or capsules.
Noofen (or Noophen) is the most widely used and original brand of phenibut. It is manufactured by the Latvian pharmaceutical company OlainFarm. You can view a translated package insert/leaflet of noofen on one of the company’s websites here.
Noofen is quite pricey though. A 20-pill pack costs about $35 to $40.
There are other cheaper generic brands manufactured by Russian pharmaceutical companies, such as Anvifen by AnviLab, and Phenibut/Fenibut by Ozon.
Noofen is not carried by US nootropics vendors, but it can be sourced from some legit Russian vendors. Two of the best places where you can buy noofen and other pharmaceutical-grade phenibut are RUPharma and CosmicNootropic.
How Does Phenibut Work?
Phenibut is a synthetic derivative and analogue of GABA, which functions as an inhibitory neurotransmitter. The compound is called phenibut as it has two components, a phenyl ring (pheni-) and gamma-aminobutyric acid (GABA), thus the addition of the suffix “-but”.
GABA-based drugs are known to have a calming effect on the brain. They are mainly used to relieve anxiety and promote sedation, relaxation and better sleep. However, GABA on its own is not able to penetrate the blood-brain barrier and thus has limited use. Addition of phenyl ring helps it to cross the blood-brain barrier, and so phenibut is more effective than GABA supplements.
It is essential to understand that not all drugs that act on GABA receptors are similar because GABA receptors are divided into numerous sub-groups. Phenibut acts primarily on GABA-B receptors. It has a weak action on GABA-A receptors.
Phenibut was also found to stimulate dopamine receptors as well as other receptors in the brain. That explains how it may be beneficial for a number of different conditions. Although its primary use is as an anxiolytic and nootropic, it may also help treat sleep disorders, depression, post-traumatic stress, and other conditions.
As a nootropic or cognitive enhancer, phenibut may improve memory and brain function, although it lacks solid clinical evidence that it is beneficial for cognitive functions beyond its anti-anxiety effect.
Since phenibut is not an approved medicine in most Western countries, there haven’t been many reliable studies that evaluate its optimal dosage.
Based on some of the studies and manufacturer recommendations from countries where phenibut is an approved medicine, and also based on anecdotal evidence and experiences of many nootropics users, the following are some generally accepted guidelines for administering phenibut.
- The standard dose for adults is 250mg, taken up to three times a day.
- You may take a single dose of 500-750mg once a day.
- Do not take more than 1,000mg (1g) per day.
- It is not recommended to take phenibut daily for more than one month.
- Cycling phenibut by taking one day (or more) off between doses is recommended, especially for long-term users. This reduces the chance of tolerance build-up and dependence.
- If you have been taking phenibut frequently for more than a few weeks, it is not recommended to stop taking it abruptly, otherwise, you may suffer from unpleasant withdrawal symptoms. Instead, you should gradually reduce the dosage for a couple of weeks before completely quitting it.
Safety and Side Effects
Phenibut is rather safe for this class of substances, which explains why unlike other GABA agonists it is not strictly regulated in many countries, though things may differ from country to country.
Despite being an analog of a naturally occurring amino acid and neurotransmitter (GABA), phenibut is produced synthetically and is not considered a natural substance. That means it does not qualify as a dietary supplement, although it is mild on the body.
Normally, small doses of phenibut don’t produce significant side effects, but that differs from one person to another. Some of the potential side effects include the following:
Higher doses of phenibut (over 2,000mg) can lead to serious side effects including the following:
- Cognitive and motor impairment
- Poor balance
Ironically, some users reported experiencing stimulant-like effects when taking phenibut, such as anxiety, agitation and insomnia! In fact, many anti-anxiety drugs have been known to cause anxiety in some cases, especially when taken by healthy individuals.
Women who are pregnant or breastfeeding should not take phenibut.
It is also important not to combine it with alcohol, benzodiazepines, or any other GABA agonist substance. If you take any kind of antidepressant or anti-anxiety medications, then it is highly advised that you consult with your doctor before taking phenibut.
Like many other substances that affect the working of the brain, phenibut can potentially lead to dependence and addiction if abused. It should be used moderately and in small doses.
Natural Alternatives to Phenibut
Although phenibut is a potent anxiety reducer that works for almost everyone, it does come with one major downside: it causes dependence with repeated use.
People who take phenibut on a daily basis will likely suffer from debilitating anxiety, agitation and other withdrawal symptoms when they try to quit phenibut. This is especially a struggle for abusers who take many grams a day of this substance.
While most natural supplements are nowhere near as effective as phenibut, there are several worthy alternatives that have worked for a considerable number of people.
The following are three of the best natural formulas that can be used in place of phenibut for a more relaxed day and restful sleep at night.
1. Anxiety Balance
Anxiety Balance by Priority One Nutritional Supplements is a blend of medicinal herbs, vitamins and natural substances that have been shown to reduce anxiety and stress.
This is an all-in-one supplement that contains several of the best natural anxiety aids that have a considerable efficacy rate.
Here’s the list of the active ingredients:
- Thiamine HCL (vitamin B1) (25mg)
- Niacin (as niacinamide) (25mg)
- Magnesium (citrate, oxide) (5mg)
- Griffonia Simplicifolia (seed) (98% 5-HTP) (75mg)
- Gamma-AminoButyric Acid (GABA) (100mg)
- Lemon Balm (leaf extract) (80mg)
- Inositol (95mg)
- Hops Extract (4:1) (13mg)
- L-Glutamic Acid (25mg)
- Passionflower (whole herb extract 4:1) (7mg)
- Rhodiola Rosea (rhizome standardized extract 4% rosavins) (50mg)
- Jujube (seed standardized extract 2% jujuboside) (50mg)
This supplement is a little pricey at $72 per bottle (90 vegetarian capsules). The recommended daily serving is one capsule. You can buy Anxiety Balance from PureFormulas.
2. Theanine Serene with Relora
Theanine Serene with Relora is a natural calming formula by Source Naturals. It contains two powerful relaxing compounds: L-theanine and Relora, in addition to a few other potent anti-anxiety ingredients.
Relora is a proprietary blend of a patented extract from magnolia bark and a phellodendron bark extract. Relora has been shown to help reduce stress and anxiety and may lower cortisol levels.
Here is the full list of active ingredients:
- Magnesium (as chelate) (300mg)
- GABA (500mg)
- Taurine (450mg)
- L-Theanine (200mg)
- Relora (150mg)
- Holy Basil (leaf extract) (100mg)
Theanine Serene with Relora costs $28 for a bottle of 120 tablets. You can buy it from PureFormulas.
3. Relax-All Sleep Aid
Relax-All Sleep Aid by MRM is a blend of herbal and nutritional compounds that promote relaxation, calmness and sleep. It combines several of the most effective anti-anxiety and anti-stress ingredients making it a perfect nighttime supplement.
Relax-All comes in powder (peach flavor) and capsule form. The powder can be mixed with cold or hot water/juice.
List of ingredients:
- Magnesium (from marine magnesium) (200mg)
- Calcium (as citrate) (100mg)
- Jujube (seed extract 2% jujubosides) (800mg)
- Gamma-Aminobutyric Acid (GABA) (750mg)
- Valerian (root extract 0.8% valeric acid) (500mg)
- Sensoril Ashwagandha (root and leaf extract 10% withanolides) (200mg)
- Inositol (200mg)
- L-Theanine (150mg)
- Chamomile Flowers (150mg)
- Lemon Balm Leaf (150mg)
One container of Relax-All Sleep Aid powder contains 30 servings and costs $20. You can buy it from PureFormulas.