Adrafinil is one of the most widely used nootropics (cognitive enhancers) that can be legally bought without a prescription in most countries. This over-the-counter drug is a precursor for modafinil, to which it gets converted after it is metabolized in the liver. But unlike modafinil, adrafinil is not currently approved to treat any health condition.
Often dubbed “smart drugs”, these stimulant substances have exploded in popularity over the past decade, so much so that it has been reported that one in four students at British universities used modafinil to boost their cognitive performance.
Adrafinil is a milder, non-Rx version of modafinil that is more commonly sold as an unregulated nootropic supplement, although it doesn’t quite qualify as a dietary supplement. While mostly not available at local stores, adrafinil can be easily sourced from numerous reliable online outlets at reasonable prices. Just ask your resourceful best friend: The Internet!
The following is a list of ten of the best places where you can safely buy pure adrafinil in powder or capsule form.
Before You Buy: Adrafinil is most effective for people suffering from fatigue, sleepiness and low energy as a result of poor/lack of sleep. It may not have any noticeable effect in healthy individuals, although results vary for each user. Adrafinil is not approved by the FDA and should not be used to treat or prevent any medical condition. Consult with your doctor for advice before taking any drug or supplement.
|Vendor||Capsule Price||Powder Price|
|Nootropics Depot||$25.99 (30 x 300mg)||$14.99 (5g)|
|Note: A one-stop shop with excellent quality control and service. The owner is active on Reddit and the company is very reputable there.|
|Pure Nootropics||$25.99 (30 x 300mg)||$33.99 (15g)|
|Note: Outstanding customer service and helpful with shipping issues. Third-party lab testing.|
|Health Naturals||$18.94 (30 x 300mg)||[No powder]|
|Note: Low prices and good quality. Only ships to the US and Canada.|
|Double Wood Supplements||$29.95 (30 x 300mg)||[No powder]|
|Note: Prompt customer service and free delivery; USA only — they don’t ship to other countries.|
|AntiAging Store||$27.99 (40 x 300mg)||[No powder]|
|Note: Their adrafinil (Adra-Pro) is in clearance mode. They do sell modafinil (Moda-Pro).|
|NewMind||[No capsules]||$15.88 (5g)|
|Note: They require an “approved account” if you want to order more than 5 grams.|
|Peak Nootropics||[No capsules]||$32.99 (10g)|
|Note: A long-standing supplier, although their popularity has been decreasing. Customer support can be slow sometimes.|
|Intellimeds||$24.12 (20 x 150mg)||$27.80 (5g)|
|Note: They ship from the EU, meaning faster delivery for customers in Europe and the UK. Their prices are very high though.|
|Nootropic Source||[No capsules]||$14.59 (5g)|
|Note: A rising vendor, but their products are labeled for lab use only. They often have issues with credit card payments.|
|xNootropics||€25.20 (30 x 100mg)||€22.00 (5g)|
|Note: A new vendor based in Malaga, Spain. No 3rd party testing, but they have some positive reviews. They only accept bitcoin, bank transfer and Western Union.|
Is it Legal to Buy Adrafinil Online?
Adrafinil is an unscheduled and unregulated drug. So that means yes, you can legally buy it from local or online suppliers for your personal use.
However, keep in mind that adrafinil is not an approved treatment, so it should not be used to treat any health condition. For diagnosed disorders, like narcolepsy and excessive daytime sleepiness, your doctor will probably prescribe you modafinil (adrafinil’s metabolite), which is a prescription-only medication.
What is Adrafinil?
Adrafinil is a drug which promotes wakefulness. In technical terms, it is a member of the eugeroic group of drugs. It was discovered in the 1970s by a pharmaceutical company in France called Lafon.
After going through various test and trial processes it was approved for marketing under the brand name Olmifon, which was discontinued in 2011, about a decade after Lafon was acquired by Cephalon. Adrafinil is now being sold in generic form, and there are some branded generic versions of this drug on the market as well.
All of adrafinil’s effects are attributed to its primary active metabolite modafinil. In other words, both of these drugs seem to have the same effects and mechanism of action in the human body, although efficacy and tolerance of each compound may vary from one user to another.
Adrafinil stimulates the central nervous system (CNS). Through the CNS it also affects the adrenergic system which is responsible for raised levels of adrenaline in situations of fear and tension. Adrafinil seems to positively affect the levels of the neurotransmitter hypocretin, which is believed to be responsible for most of the focus and wake promoting benefits.
Hypocretin, aka orexin, is linked directly to the wakefulness effect. At the same time, increased levels of hypocretin cause raised levels of other neurotransmitters like dopamine and histamine. It inhibits the breakdown of natural dopamine and thus helps sustain a good mood and reduces feeling of stress. Adrafinil has also been suggested to promote learning abilities, improve memory, and enhance overall brain activity, although these claims lack scientific evidence.
Some of the end results that are reported by adrafinil users include:
- Promotes alertness.
- Improves ability to concentrate mentally.
- Reduces the tendency of drowsiness.
- Mitigates the feeling of fatigue.
As for its “nootropic” effect, there is no evidence that adrafinil helps healthy individuals who do not suffer from sleep-wake problems, but in general, it may enhance some cognitive functions, like:
Adrafinil and its metabolite modafinil are gainfully used by different people in various situations. Most common users include:
- Shift workers can benefit from increased alertness and reduced fatigue.
- People who don’t get enough sleep or who need to stay awake for prolonged/odd hours may find it helpful.
- Students may benefit from the nootropic effect, which may help them stay focused and better retain information, but don’t count on it really!
- People with poor attention may see improvement in symptoms and behaviors.
At present, adrafinil is an unapproved, over-the-counter drug in the USA and worldwide in general. It can be bought as desired without a doctor’s prescription, and it is treated as a supplement.
Generic adrafinil supplements can be purchased online from many nootropics sellers, and it is available in powder form as well as capsules (usually in standard 300mg doses).
Adrafinil is not a controlled or scheduled substance, so buying and importing it is legal for personal use or research, but because it is not approved by the FDA, it cannot be sold, nor should it be used, as a treatment for any illness or disease.
Starting dose can range from 100 mg to 300 mg, with 300 mg being the standard daily dose. Because everyone’s body responds differently, a higher dosage may be needed by some individuals to achieve remarkable results. The dose can be gradually increased to a maximum of 1,200 mg a day.
It is safer to keep your daily consumption within the 300-600 mg range. In case you reach 1,200 mg and still don’t notice effects, then you are probably a nonresponder, and increasing the dosage beyond 1,200 mg may be futile and potentially risky.
How to Use Adrafinil
Adrafinil powder has low solubility in water, but small amounts may completely dissolve in warm water. If you use the powder, you can mix the required dose with water or some citrus juice to mask the bitter taste of the substance.
Alternatively, capsules are more convenient to use as all you have to do is swallow the tasteless capsule with some water.
Many users reported best results when the dose is taken first thing in the morning on an empty stomach. You can try different timings and see what works best for you. Food is optional, but keep in mind that heavy meals may reduce the absorption and effectiveness of the drug.
Continuous long-term use is not recommended because of a possibility of developing tolerance, and potential side effects.
Tolerance means that the body may get used to the drug and give a reduced or no response at all with repeated use. Weekly on/off cycles are recommended. That is, take it 3-4 times for a week and abstain for the following week.
There are also some concerns about liver toxicity associated with prolonged use and overdosing. Adrafinil – like many other drugs, alcohol and toxins – is broken down in the liver. This process causes a rise in liver enzymes needed to metabolize the drug.
Taking adrafinil daily for a long period of time may make your liver less efficient at breaking down other drugs, alcohol and toxins. But again, this also applies to alcohol and any other substance that is metabolized in the liver.
Adrafinil should be taken sparsely and only when needed. This may not be the best choice for an everyday supplement.
It is always preferable to speak with your physician before embarking on long-term use of any nootropic drug.
Possible Side Effects
Like all drugs, adrafinil has some potential side effects. Most common side effects may include:
- Sleep issues
- Decreased appetite
Some less common side effects are:
- Getting bruised easily
- Heart palpitations and/or chest pain — any such feeling must be taken seriously and discussed with your physician.
- High blood pressure — people with cardiovascular disease should be extra cautious.
Liver disorders may result from long-term use. Liver function should be monitored regularly. Patients with pre-existing liver disorders should avoid taking adrafinil without consulting with their physician.
There was also one reported case of a facial movement disorder called orofacial dyskinesia that seems to have been induced by adrafinil.
Adrafinil is a relatively safe stimulant nootropic with very few and mild side effects, but that does not mean you shouldn’t use it with caution.